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Magazine of the plasma protein therapeutics industry - Summer 2013

Magazine of the plasma protein therapeutics industry - Spring 2013

Magazine of the plasma protein therapeutics industry - Winter 2012

Following the meeting of the Blood Commission on November 16, 2011, where the Amrein et al. study of plateletpheresis donors that reported bone mineral density (BMD) losses at one of three skeletal sites was associated with donating platelets1 was discussed, the Plasma Protein Therapeutics Association (PPTA) was asked to respond to the suggestion that Source Plasma donors, with their high-frequency, high-volume donations, were at risk of BMD loss. The industry has evaluated the Amrein et al. study, conducted extensive literature surveys to see if similar findings had been published, and assessed risk to plasma donors looking at the comparison of the exposures to citrate that plasma and platelet donors would receive during the apheresis collection process. The result of this analysis is presented in this paper to address the Blood Commission’s concerns.